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Los Angeles Thermo Scientific HPLC Calibration

Specializing in Thermo Scientific HPLC calibration and certification services, biopharmaceutical and medical companies throughout Los Angeles rely on the experts at GL Technologies for their laboratory equipment needs. If you're in the market for a high-performance liquid chromatography (HPLC) calibration company in Los Angeles, you have many options. Not all calibration companies are created equal, when it comes to accuracy, reliability, and expertise, GL Technologies is the name you can trust.

To speak with the experts about your Thermo Scientific HPLC needs, please fill out our online form or give us a call!


The Experts in Thermo Scientific HPLC Calibrations

GL Technologies HPLC calibration services of Thermo Scientific equipment include instrument performance verification, system suitability testing, and calibration documentation to meet regulatory requirements. We also offer a range of calibration and maintenance options to ensure your HPLC system is running smoothly and efficiently.

In addition to their HPLC calibration services, GL Technologies offers a variety of products, including chromatography systems, mass spectrometry systems, and sample preparation certifications.

If you're looking for a Los Angeles Thermo Scientific HPLC calibration company that you can trust, look no further than GL Technologies. Our commitment to accuracy, reliability, and customer service make us the top choice for biopharmaceutical and medical HPLC calibration services in Los Angeles and beyond.

Importance of HPLC Calibration

Calibration in HPLC involves adjusting and validating the system to ensure accurate and consistent results. Thermo Scientific HPLC systems, renowned for their sensitivity and precision, require meticulous calibration to maintain their performance standards. The calibration process involves fine-tuning various components, such as detectors, pumps, columns, and software, to align with specified parameters. This meticulous calibration guarantees reliable and reproducible analytical data, vital for critical decision-making in research, quality control, and manufacturing processes.

Components Involved in HPLC Calibration

Pumps and Injectors

Thermo Scientific HPLC systems utilize pumps to deliver solvents at precise flow rates. Calibration ensures these pumps function accurately, providing consistent flow rates critical for separation and analysis. Injectors, responsible for introducing samples into the chromatographic system, require calibration to ensure precise and reproducible sample volumes.


The detectors in Thermo Scientific HPLC systems, such as UV-Vis detectors or mass spectrometers, must be calibrated to accurately measure and quantify analytes. Calibration optimizes sensitivity, linearity, and accuracy, crucial for precise compound identification and quantification.


Columns are at the heart of chromatographic separation. Calibration involves proper conditioning and validation of columns, ensuring optimal resolution and separation efficiency.

Software and Data Handling

Thermo Scientific's software plays a pivotal role in controlling and analyzing data. Calibration involves verifying and validating software settings to ensure accurate data acquisition, processing, and reporting.

Benefits of Thermo Scientific HPLC Calibration

Proper calibration of Thermo Scientific HPLC systems offers several advantages:


Calibration is vital as it fine-tunes instrument parameters, such as flow rate, detector sensitivity, and retention times, establishing a reliable baseline for precise analysis. This accuracy is important in quantitative determinations, as it improves the system's ability to differentiate between compounds, improves peak resolution, and guarantees the precision of results obtained during sample analysis. Thermo Scientific's calibrated HPLC systems not only elevate the quality of data output but also provide a heightened level of confidence in scientific conclusions


By adhering to strict calibration protocols, Thermo Scientific calibration guarantees exact retention times, peak resolution, and accurate quantification, important for obtaining dependable and reproducible results in complex analysis. This reliability not only increases the quality of experimental outcomes but also instills confidence in researchers and laboratories, creating trust in their data, methodologies, and contributing to advancements in scientific research and development across various industries.


By calibrating Thermo Scientific HPLC instruments, GL Technologies not only guarantees accuracy and precision in analytical results but also fortifies adherence to strict regulatory standards. The calibration protocols embedded within these systems facilitate the meticulous alignment of detectors, pumps, and other critical components, thereby maximizing the instrument's performance and increasing the reliability of generated data.

Cost Savings

By maintaining the accuracy of measurements, it significantly reduces the risk of erroneous results and rework, preventing costly material wastage and time-consuming repetitions. Calibrated HPLC systems operate at peak efficiency, diminishing the likelihood of unexpected breakdowns or malfunctions, consequently lowering expenses associated with repairs and replacements.

Peak Performance

By fine-tuning critical parameters such as flow rates, detector sensitivity, and gradient accuracy, it guarantees the reproducibility of analysis, maintaining consistent and dependable outcomes. This peak performance not only boosts productivity by reducing downtime for troubleshooting but also instills confidence in the validity of data obtained, meeting the strict demands of various industries reliant on high-performance liquid chromatography (HPLC) for critical analytical processes.

Popular HPLC Articles

HPLC Calibration: Accuracy in Analytical Chemistry

Analytical chemistry plays an important role in various scientific fields, from pharmaceuticals to environmental monitoring, where precision and accuracy are paramount. High-Performance Liquid Chromatography (HPLC) stands as a cornerstone technique in analytical chemistry, allowing for the separation, identification, and quantification of components in complex mixtures. The reliability of HPLC results heavily relies on the proper calibration of equipment and attention to detail. Calibration is a process that verifies the accuracy, precision, and reliability of the HPLC system, protecting against errors that could compromise data integrity. Let's look at the significance of HPLC calibration, its key components, and the methods used to maintain accuracy in analytical chemistry.

Fine-tuning HPLC Calibration for Biopharma Excellence

In the evolving world of biopharmaceuticals, High-Performance Liquid Chromatography (HPLC) stands as a pillar analytical technique. It allows for the separation, identification, and quantification of compounds that are vital to the development, production, and quality control of biopharmaceuticals. HPLC calibration plays a role in maintaining the accuracy, reliability, and excellence of analytical results in this industry.

About GL Technologies

As a full-service company specializing in equipment calibration, repair, and certification services for biopharmaceutical, pharmaceutical, and medical device industries. Our team has extensive experience working with sPRT calibrations along with CMMS softwareHPLC OQ validation, and fume hood certifications. Companies of all sizes rely on our team to implement, maintain, and keep their research and manufacturing processes compliant with regulatory standards. Other specialties include building maintenance systems, and mass spectrometry calibrations.

To speak with the experts about your Thermo Scientific HPLC needs, please fill out our online form or give us a call!



To request a quote from GL-Tec, please fill out our online form and we will get back to you promptly.


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