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sPRT Calibration

In biopharmaceutical manufacturing, precision and accuracy are critical. The reliable measurement of temperature is important to maintain the quality and safety of biopharmaceutical products. To provide accurate temperature measurements, the calibration of temperature sensors like the standard platinum resistance thermometers (sPRTs), is vital. GL Technologies works with biopharmaceutical organizations throughout California for their equipment calibration needs including sPRT's. We are experts in biopharma manufacturingand our clients rely on us to keep them compliant with regulatory agencies and their products safe and effective.

To speak with the experts about your sPRT calibration needs, please fill out our online form or give us a call!


Significance of sPRT in BioPharma

Understanding sPRT Calibration

sPRTs are widely used in biopharma manufacturing because of their stability, linearity, and accuracy. These sensors operate on the principle of the temperature-dependent resistance of a platinum wire. sPRTs require regular calibration to maintain their accuracy against a reference standard.

Calibration involves comparing the resistance values of the sPRT at various known temperatures against the reference standard. By establishing a calibration curve, the relationship between temperature and resistance is determined providing exact temperature measurements during biopharma processes.

Maintaining Product Quality and Safety

For biopharmaceutical manufacturing, maintaining strict temperature control is important for product quality and safety. Most bioprocesses including fermentation, cell culture, and protein purifications are temperature-sensitive. A slight deviation from the required temperature range can impact product yield and purity.

By calibrating sPRTs, manufacturers can accurately monitor and control temperature conditions. This improves process conditions, minimizes the risk of product variability, and improves batch-to-batch consistency. Accurate temperature measurements also contribute to meeting regulatory standards and reduce potential non-compliance issues.

Regulatory Compliance

Biopharmaceutical manufacturing is subject to strict regulations and guidelines set forth by the FDA to emphasize the importance of accurate temperature control and monitoring throughout the manufacturing process.

Calibration of sPRTs is a fundamental aspect of maintaining compliance. Regulatory agencies require documented evidence of sensor calibration as part of their inspections. By having a calibration program in place, organization's can demonstrate their commitment to quality and patient safety.

Cost Reduction and Efficiency

While the goal of sPRT calibration is to verify accuracy, it also has cost-saving implications. Accurate temperature measurements contribute to efficient energy usage and minimizes resource waste. By maintaining exact temperature control, biopharma manufacturer's can improve overall process efficiency and reduce cycle times.

Regular calibration also helps to identify any drft or deviations in sensor performance. Early detection of potential issues allow or quick sensor maintenance or replacement, preventing potential process disruptions and costly downtime.

sPRT Popular Articles

How sPRTs Improve Biopharmaceutical Manufacturing

The biopharmaceutical industry has witnessed remarkable advancements in recent years, drastically changing the way we treat diseases and improve patient care. One significant breakthrough that has changed the manufacturing process is the use of Single-Use Pressure Sensors (sPRTs). These sensors have proven to play a vital role increasing efficiency, improving quality, and reducing costs in biopharmaceutical production.

Temperature Accuracy in Biopharma: The Crucial Role of sPRTs

In the world of biopharmaceuticals where precision and reliability are of the utmost importance, temperature monitoring stands as a linchpin for verifying the potency and safety of products. Within this domain, the significance of Standard Platinum Resistance Thermometers (sPRTs) cannot be overstated. These highly precise temperature sensors play a role in maintaining the integrity of sensitive biopharmaceutical processes, protecting both quality and compliance standards.

To speak with the experts about your sPRT calibration needs, please fill out our online form or give us a call!


About GL Technologies

As a full-service company specializing in equipment calibration, repair, and certification services for biopharmaceutical, pharmaceutical, and medical device industries. Our team has extensive experience working with sPRT calibrations along with CMMS softwareHPLC OQ validation, and fume hood certifications. Companies of all sizes rely on our team to implement, maintain, and keep their research and manufacturing processes compliant with regulatory standards. Other specialties include building maintenance systems, and mass spectrometry calibrations.  GL Technologies provides sPRT calibration services to clients throughout California including San Diego, Los Angeles, and San Francisco just to name a few locations that our clients facilities are in.


To request a quote from GL-Tec, please fill out our online form and we will get back to you promptly.


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