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How sPRTs Improve Biopharmaceutical Manufacturing

The biopharmaceutical industry has witnessed remarkable advancements in recent years, drastically changing the way we treat diseases and improve patient care. One significant breakthrough that has changed the manufacturing process is the use of Single-Use Pressure Sensors (sPRTs). These sensors have proven to play a vital role increasing efficiency, improving quality, and reducing costs in biopharmaceutical production.

Traditional manufacturing processes in biopharma often involved stainless-steel equipment and fixed systems that required extensive cleaning and validation between each use. With the emergence of single-use technologies, including sPRTs, has completely changed this landscape by offering a more streamlined and flexible approach.

What Are sPRTs?

Single-Use Pressure Sensors (sPRTs) are compact, disposable devices designed to measure and monitor pressure accurately during various stages of biopharmaceutical manufacturing. These sensors are integrated into single-use bioprocessing systems, allowing for real-time monitoring without the need for complex setups or cleaning procedures.

Advantages of sPRTs in Biopharmaceutical Manufacturing

Flexibility and Scalability

One of the primary advantages of sPRTs is their ability to adapt to different scales of production. Whether it's small-scale research or large-scale manufacturing, these sensors can be easily integrated into the bioprocess, offering flexibility and scalability without compromising accuracy.

Reduced Contamination Risks

With traditional stainless-steel equipment, the risk of cross-contamination between batches was a significant concern. sPRTs minimize this risk by being disposable. Their single-use nature eliminates the need for cleaning and sterilization, maintaining a higher level of product safety and quality.


Implementing single-use technologies like sPRTs can result in cost savings by reducing capital expenditure associated with stainless-steel infrastructure. The elimination of cleaning validation processes and reduced downtime contributes to overall cost-effectiveness in manufacturing operations.

Process Control and Efficiency

Real-time monitoring provided by sPRTs allows for precise control over critical process parameters. This increases process efficiency by allowing for rapid adjustments, maximizing yields, and maintaining product quality throughout the production cycle.

Environmental Sustainability

The use of single-use technologies aligns with sustainability goals by minimizing water and energy consumption associated with cleaning and sterilization processes. The disposability of sPRTs reduces the generation of hazardous waste.

Future Outlook

As the biopharmaceutical industry continues to evolve, the adoption of single-use technologies like sPRTs is expected to grow rapidly. Ongoing innovations in sensor technology will likely lead to even more advanced and sophisticated monitoring capabilities, further improving manufacturing efficiency and product quality.

About GL Technologies

As a full-service company specializing in equipment calibration, repair, and certification services for biopharmaceutical, pharmaceutical, and medical device industries. Our team has extensive experience working with sPRT calibrations along with CMMS softwareHPLC OQ validation, and fume hood certifications. Companies of all sizes rely on our team to implement, maintain, and keep their research and manufacturing processes compliant with regulatory standards. Other specialties include building maintenance systems, and mass spectrometry calibrations

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