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San Francisco Mass Spectrometry Calibration Services

San Francisco has long been recognized as a global hub for innovation and technology. This thriving city is also home to a variety of biotech and pharmaceutical companies, contributing to the growth of the biopharmaceutical sector. WIth this massive region of research, biopharma and medical related industries rely on the GL Technologies team for mass spectrometry calibration and certification services. We have carved out a niche in offering precision calibration services for mass spectrometry instruments.

To speak with the experts about your mass spec needs, please fill out our online form or give us a call!


A Leader in Mass Spectrometry Calibration

Our San Francisco biopharmaceutical mass spectrometry calibration team has emerged as a leading provider of calibration services for the biopharmaceutical industry. GL Technologies distinguishes itself through several unique features:

Expertise: GL-Tec employs a team of highly skilled and experienced technicians, ensuring the highest level of expertise in mass spectrometry calibration.

Advanced technology: We utilizes state-of-the-art technology and equipment to deliver accurate, precise, and reliable calibration services.

Comprehensive services: GL Technologies offers a wide range of calibration services, including mass accuracy, resolution, sensitivity, and more, catering to the diverse needs of the biopharmaceutical industry.

Customer-centric approach: Prioritizes customer satisfaction, providing personalized services and support to meet the unique needs of each client.

Quality assurance: Adhere to strict quality control measures, ensuring that all calibrations meet industry standards and regulatory requirements.

GL Technologies is changing the biopharmaceutical industry by offering exceptional calibration services for mass spectrometry instruments. With a commitment to accuracy, efficiency, and customer satisfaction, we are paving the way for a new era in biopharmaceutical analytics. By partnering with GL-Tec, biopharmaceutical companies can unlock the full potential of their mass spectrometry instruments and deliver high-quality products that improve the lives of patients around the world.

Key Advantages Include

Accuracy and Precision

Accuracy in mass spectrometry calibration guarantees that the instrument correctly identifies and quantifies compounds present in biopharmaceutical samples, leading to reliable results. Precision, on the other hand, makes sure there are consistent and reproducible measurements for assessing the purity, concentration, and structural elucidation of complex biomolecules within drug formulations. Calibration processes fine-tune the instrument settings, minimizing deviations and improving the instrument's ability to differentiate between molecules with similar masses, strengthening the reliability of biopharmaceutical analyses and supporting the quality control process within the industry.

Quality Control

Accurate calibration aids in the identification of impurities, trace elements, and structural variants in biopharmaceuticals, maintaing adherence to strict regulatory requirements. Calibration routines facilitate instrument performance validation, providing reproducibility across multiple analytical runs, strengthening the confidence in the production of high-quality biopharmaceutical products.

Quantitative Analysis

Calibration procedures in mass spectrometry allow for precise determination of compound concentrations, facilitating critical assessments in drug development, quality control, and discovery. Through calibration, mass spectrometers can accurately measure the mass-to-charge ratios of ions, allowing for the quantification of specific molecules or compounds within complex biological samples.

Method Development and Validation

Method development and validation in mass spectrometry calibration play an important role in improving the sensitivity and specificity of the instrumentation used for characterizing biomolecules and pharmaceutical compounds. The calibration process allows for the establishment of standardized protocols, providing consistent and reproducible results across different analytical platforms. Through method development, scientists and researchers can fine-tune parameters, such as ionization techniques, mass-to-charge ratios, and fragmentation patterns, improving the instrument's performance for the specific molecules under investigation. Validation, on the other hand, assesses the accuracy and linearity of the developed method, making sure its suitability for exact quantification and identification of target compounds.

Sensitivity and Specificity

Increased sensitivity allows for the identification and quantification of low-abundance biomolecules, such as proteins, peptides, metabolites, and drug compounds, vital in biopharmaceutical research and development. Calibration aids in achieving higher specificity by accurately distinguishing between different compounds with similar masses, minimizing false positives and negatives. This increased accuracy not only refines analytical results but also facilitates the complex molecular structures

Batch Consistency and Product Integrity

This calibration process maintains the accuracy of analytical results, allowing for the detection of impurities, modifications, or variations in biopharma products across different batches. The calibration also aids in the validation of manufacturing processes, guaranteeing uniformity in product quality and performance. Mass spectrometry calibration serves as an indispensable tool for maintaining the strict standards required in biopharmaceutical and pharmaceutical development, allowing for the consistent delivery of safe and effective therapies to patients while meeting regulatory requirements.

Mass Spec Education

Mass Spectrometry's Role in Advancing Biopharmaceutical Analysis

In the biopharmaceutical industry, the quest for more effective therapies is a driving force behind scientific innovation. With the continued rise of biologics and the increasing complexity of drug formulations, analytical techniques have had to evolve to keep pace with industry demands. Mass spectrometry is a powerful analytical tool that has emerged as a pivotal technology in advancing biopharma analysis. Let’s explore the role mass spectrometry plays in the development, quality control, and safety assessment of biopharmaceuticals and pharmaceuticals.

The Importance of Mass Spectrometry

Mass spectrometry is a powerful analytical tool used in the biopharmaceutical industry to determine the identity and quantity of protein and peptide therapeutics. However, accurate quantification of these complex molecules can be challenging due to variability in the mass spectrometer's performance over time. To ensure reliable results, regular calibration of the mass spectrometer is essential. Calibration is the process of verifying and adjusting the accuracy of the mass spectrometer. Calibration ensures that the instrument is performing as expected and producing accurate and reproducible results. Calibration is critical for biopharmaceuticals because even small errors in mass measurement can have significant consequences in determining the identity and purity of the drug product.

About GL Technologies

As a full-service company specializing in equipment calibration, repair, and certification services for biopharmaceutical, pharmaceutical, and medical device industries. Our team has extensive experience working with sPRT calibrations along with CMMS softwareHPLC OQ validation, and fume hood certifications. Companies of all sizes rely on our team to implement, maintain, and keep their research and manufacturing processes compliant with regulatory standards. Other specialties include building maintenance systems, and mass spectrometry calibrations.

To speak with the experts about your mass spec needs, please fill out our online form or give us a call!



To request a quote from GL-Tec, please fill out our online form and we will get back to you promptly.


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